University of Texas Southwestern Medical Center
David Sher
To determine the risk of solitary elective volume recurrence following involved nodal radiotherapy (INRT) versus elective nodal irradiation (ENI)
Head and Neck Cancer
ENI using IMRT with or without chemotherapy
INRT
ENI
PHASE2
Patients are assigned to either elective nodal irradiation (ENI), the current treatment paradigm, or involved nodal radiotherapy (INRT), the experimental treatment. INRT is more specifically targeting potentially cancerous nodes, identified using an AI program developed in-house. The hope is that this more specific targeting will decrease healthy tissue being irradiated, therefore decreasing potential side effects of the radiation treatment. Patients are blinded during study participation.
Study Type : | INTERVENTIONAL |
Estimated Enrollment : | 80 participants |
Masking : | SINGLE |
Masking Description : | Patients are blinded to their treatment. |
Primary Purpose : | TREATMENT |
Official Title : | INVERT - Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy |
Actual Study Start Date : | 2024-11-14 |
Estimated Primary Completion Date : | 2028-07-01 |
Estimated Study Completion Date : | 2028-07-01 |
Information not available for Arms and Intervention/treatment
Ages Eligible for Study: | 18 Years to 99 Years |
Sexes Eligible for Study: | ALL |
Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
UT Southwestern Medical Center
Dallas, Texas, United States, 75390