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NCT06461689 | NOT YET RECRUITING | Prostate Cancer Metastatic


Comparison of Changes in Tumor Burden in 68Ga-PSMA-11 PET/CT and 177Lu-PSMA SPECT/CT in Metastatic Castration-resistant Prostate Cancer
Sponsor:

Central Hospital, Nancy, France

Information provided by (Responsible Party):

SCHOLARSHIP Caroline

Brief Summary:

To demonstrate the prognostic value of using post-therapy 177Lu-PSMA SPECT/CT versus 68Ga-PSMA-11 PET/CT in mCPRC patients progressing despite chemotherapy and treated with 177Lu-PSMA.

Condition or disease

Prostate Cancer Metastatic

Intervention/treatment

177Lu-PSMA-617

Detailed Description:

Since few years, therapy by 177Lu-PSMA in nancy hospital began. A lot's of datas were collected. Prostate cancer is the number one killer in france and this is very important to find a diagnostic tool. The hypothesis of this study is to demonstrate the prognostic value of using post-therapy 177Lu-PSMA SPECT/CT versus 68Ga-PSMA-11 PET/CT in mCPRC patients progressing despite chemotherapy and treated with 177Lu-PSMA.

Study Type : OBSERVATIONAL
Estimated Enrollment : 80 participants
Official Title : Comparison of Changes in Tumor Burden (Toral Tumor Volume [TMTV] and Total Lesion Activity [TLA]) in 68Ga-PSMA-11 PET/CT and 177Lu-PSMA SPECT/CT in the Monitoring of Metastatic Castration-resistant Prostate Cancer Treated With 177Lutetium-PSMA-617
Actual Study Start Date : 2025-01-31
Estimated Primary Completion Date : 2025-09-01
Estimated Study Completion Date : 2026-03-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Criteria
Inclusion Criteria
  • * patient who received a dose of 177lu-PSMA
  • * patient who had imaging by 68Ga-PSMA
  • * patient treated in Nancy hospital for its cancer prostate
Exclusion Criteria
  • * no social security
  • * no acceptation to participating in retrospective study

Comparison of Changes in Tumor Burden in 68Ga-PSMA-11 PET/CT and 177Lu-PSMA SPECT/CT in Metastatic Castration-resistant Prostate Cancer

Location Details

NCT06461689


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Locations


Not yet recruiting

France,

CHRU de NANCY

Vandoeuvre les Nancy cedex, France, 54511

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