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NCT06451874 | NOT YET RECRUITING | Motoric Cognitive Risk Syndrome

Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome
Sponsor:

VA Office of Research and Development

Brief Summary:

This study will begin to evaluate personalized preventative dementia treatments for Veterans at risk for developing dementia. The investigators will target Veterans with Motoric Cognitive Risk syndrome (MCR), which is characterized by slow gait speed and cognitive concerns (e.g., problems with memory or concentrations).

Condition or disease

Motoric Cognitive Risk Syndrome

Intervention/treatment

Functional Power Training (FPT)

Music-Based Digital Therapy (MBDT)

FPT + MBDT

Phase

NA

Detailed Description:

This study will involve therapeutic exercise treatments for Veterans with pre-clinical dementia syndrome. Participants will either participate in functional power training, music-based walking training, or a combination of both. The study will use a sequential multiple assignment, randomized trial (SMART) design. Successful completion of this study will lay the foundation for subsequent research trials, contributing to valuable evidence for personalized rehabilitation medicine for older Veterans.

Study Type : INTERVENTIONAL
Estimated Enrollment : 54 participants
Masking : NONE
Primary Purpose : PREVENTION
Official Title : Motoric Cognitive Risk Syndrome: Refining Treatment Strategies and Testing Feasibility to Personalize Treatment for Older Veterans
Actual Study Start Date : 2025-06-01
Estimated Primary Completion Date : 2029-05-31
Estimated Study Completion Date : 2029-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 65 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • 1. Age 65
  • 2. Receiving VA primary care
  • 3. Community-dwelling
  • 4. Motoric Cognitive Risky Syndrome i. Slow gait speed ii. Subjective cognitive concerns/complaints
Exclusion Criteria
  • 1. Non-English speaking
  • 2. Presence of a terminal disease
  • 3. Major medical problem
  • 4. Myocardial infarction or major surgery in the previous 3 months
  • 5. Use of a walker
  • 6. Dementia diagnostic
  • 7. Mobility disability
Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome

Location Details

NCT06451874

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

Not yet recruiting

United States, Massachusetts

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Boston, Massachusetts, United States, 02130-4817