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NCT06400550 | RECRUITING | Melanoma (Skin)


Identification of Metabolic Phenotypes Associated With Melanoma Metastasis
Sponsor:

University of Texas Southwestern Medical Center

Information provided by (Responsible Party):

Jennifer Gill

Brief Summary:

The goal of this study is to observe metabolic features associated with human melanoma tumors.

Condition or disease

Melanoma (Skin)

Detailed Description:

This is a single center, correlative study designed to assess metabolic features of melanoma tumors in patients. The study will involve the collection of melanoma tissue at the time of surgical biopsy or excision. All samples will be assessed by mass spectrometry for metabolomic analysis. A subset of patients will have received \[U-13C\]glucose infusions which will be utilized for isotope tracing metabolic analysis. Relevant clinical data (eg survival, metastasis) will be correlated with metabolic findings.

Study Type : OBSERVATIONAL
Estimated Enrollment : 400 participants
Official Title : Identification of Metabolic Phenotypes Associated With Melanoma Metastasis
Actual Study Start Date : 2018-08-01
Estimated Primary Completion Date : 2028-08-01
Estimated Study Completion Date : 2028-08-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patients with known or probable malignant melanoma lesions requiring surgical biopsy or excision.
  • * Subjects of all races and ethnic origins over age 18.
Exclusion Criteria
  • * Not a surgical candidate
  • * Poorly controlled diabetes

Identification of Metabolic Phenotypes Associated With Melanoma Metastasis

Location Details

NCT06400550


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Locations


RECRUITING

United States, Texas

University of Texas Southwestern Medical Center

Dallas, Texas, United States, 75390

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