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NCT06393647 | RECRUITING | Frailty


Relationship Between Albumin/Creatine Ratio, B12, Folate, and Frailty Index
Sponsor:

Ankara Etlik City Hospital

Information provided by (Responsible Party):

Yusuf Özgüner

Brief Summary:

In the literature, the relationship between frailty and various blood tests such as beta-2 microglobulin, CRP, procalcitonin, vitamin D, IL-1, and IL-6 has been investigated (2). In our study, the investigators aim to investigate the relationship between frailty status assessed using frailty scale forms (Frailty Scale Version 9, Quality of Life Scale Short Form-36) and preoperative levels of Albumin/Creatinine, B12, Folate, Ferritin, hemogram, Sedimentation Rate, and CRP in patients undergoing gastrointestinal malignancy surgery. By identifying the relationship among these parameters, the investigators believe that modifiable factors contributing to frailty in patients at risk can be addressed through appropriate interventions.

Condition or disease

Frailty

Intervention/treatment

Frailty scale forms (Frailty Scale Version 9, Quality of Life Scale Short Form-36)

Detailed Description:

Frailty is a condition associated with a decline in physiological performance. Patients are categorized as healthy, pre-frail, or frail based on physiological and functional characteristics. Frailty is known to be influenced by various lifestyle factors such as socioeconomic status, psychological factors, diet, exercise, and genetic predisposition. With aging, there is an increase in cognitive and physical dysfunction, which correlates with an increase in frailty. Along with frailty, geriatric symptoms, mortality, and other negative health outcomes also increase in the elderly population. Therefore, early detection of frailty is crucial to implementing lifestyle changes aimed at improving cognitive and physical status. Various assessment scales are used to evaluate frailty, such as the Frailty Scale Version 9, Quality of Life Scale Short Form-36, and Modified 5-item frailty index (mFI-5) In the literature, the relationship between frailty and various blood tests such as beta-2 microglobulin, CRP, procalcitonin, vitamin D, IL-1, and IL-6 has been investigated (2). In our study, the investigators aim to investigate the relationship between frailty status assessed using frailty scale forms (Frailty Scale Version 9, Quality of Life Scale Short Form-36) and preoperative levels of Albumin/Creatinine, B12, Folate, Ferritin,hemogram, Sedimentation Rate, and CRP in patients undergoing gastrointestinal malignancy surgery. By identifying the relationship among these parameters, the investigators believe that modifiable factors contributing to frailty in patients at risk can be addressed through appropriate interventions.

Study Type : OBSERVATIONAL
Estimated Enrollment : 40 participants
Official Title : Relationship Between Albumin/Creatine Ratio, B12, Folate, and Frailty Index in Patients Undergoing Gastrointestinal Malignancy Surgery
Actual Study Start Date : 2024-06-15
Estimated Primary Completion Date : 2024-10-15
Estimated Study Completion Date : 2024-11-05

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 65 Years to 90 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patients who are over 65 years old.
  • * Patients classified under ASA (American Society of Anesthesiologists) risk groups I, II, and III.
  • * Patients with gastrointestinal malignancy undergoing surgery
Exclusion Criteria
  • * Patients who are under 65 years old.
  • * Patients with an ASA score of IV or higher.
  • * Patients who refuse to participate in the study.
  • * Patients undergoing emergency surgeries will be excluded from the study

Relationship Between Albumin/Creatine Ratio, B12, Folate, and Frailty Index

Location Details

NCT06393647


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Locations


RECRUITING

Turkey, Ankara

Yusuf

ÇANKAYA, Ankara, Turkey,

RECRUITING

Turkey, Varlık Mahallesi, Halil Sezai Erkut Street Yenimahalle

Ankara Etlik City Hospital

Ankara, Varlık Mahallesi, Halil Sezai Erkut Street Yenimahalle, Turkey, 06170

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