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NCT06327373 | NOT YET RECRUITING | Pulmonary Hypertension

A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia
Sponsor:

Duke University

Brief Summary:

The purpose of this study is to assess the feasibility of supplemental oxygen delivery during hemodialysis in people with pulmonary hypertension and intradialytic hypoxemia.

Condition or disease

Pulmonary Hypertension

Intervention/treatment

Oxygen

Room air

Phase

PHASE1

PHASE2

Study Type : INTERVENTIONAL
Estimated Enrollment : 10 participants
Masking : NONE
Primary Purpose : TREATMENT
Official Title : A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia
Actual Study Start Date : 2025-07-01
Estimated Primary Completion Date : 2026-06-30
Estimated Study Completion Date : 2026-06-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Adults ≥18 years
  • * Receiving Monday-Wednesday-Friday or Tuesday-Thursday-Saturday hemodialysis
  • * Screened positive for pulmonary hypertension (defined by tricuspid regurgitant velocity \[TRV\] \>2.5 m/s on echocardiography) and intradialytic hypoxemia (defined by spending ≥1/3 treatment with O2 saturation \<90%) or hypoxemia for ≥10% of the treatment if associated with a desaturation event (≥4% decline in O2 saturation to \<88% for ≥10 seconds) during enrollment in the PH-ESKD study (Pro00108710).
Exclusion Criteria
  • * Daily supplemental oxygen use
  • * Inability to provide informed consent
A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia

Location Details

NCT06327373

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

Not yet recruiting

United States, North Carolina

Davita Durham East

Durham, North Carolina, United States, 27701

Not yet recruiting

United States, North Carolina

Davita Durham Downtown

Durham, North Carolina, United States, 27703

Not yet recruiting

United States, North Carolina

Davita Research Triangle Park

Durham, North Carolina, United States, 27703

Not yet recruiting

United States, North Carolina

Davita Durham Regional

Durham, North Carolina, United States, 27704

Not yet recruiting

United States, North Carolina

Davita Durham West

Durham, North Carolina, United States, 27705

Not yet recruiting

United States, North Carolina

Davita Bull City

Durham, North Carolina, United States, 27707

Not yet recruiting

United States, North Carolina

Davita Durham Southpoint

Durham, North Carolina, United States, 27713

Not yet recruiting

United States, North Carolina

Davita Hope Valley

Durham, North Carolina, United States, 27713

Not yet recruiting

United States, North Carolina

Davita Vance County

Henderson, North Carolina, United States, 27536

Not yet recruiting

United States, North Carolina

Davita Kerr Lake

Henderson, North Carolina, United States, 27537

Not yet recruiting

United States, North Carolina

Davita Roxboro

Roxboro, North Carolina, United States, 27573