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NCT06275230 | Not yet recruiting | Chronic Obstructive Pulmonary Disease

Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD
Sponsor:

China-Japan Friendship Hospital

Information provided by (Responsible Party):

Gang Hou

Brief Summary:

The goal of this study is to proliferate human lung stem cell in vitro in order to establish a lung organoid derived from patients with COPD. The main question it aims to answer are: Can human lung stem cell proliferate in vitro. Can a lung organoid derived from patients with COPD be established. Participants will be sampled during pulmonary bronchoscope for organoid establishment.

Condition or disease

Chronic Obstructive Pulmonary Disease

Study Type : Observational
Estimated Enrollment : 30 participants
Official Title : Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in Chronic Obstructive Pulmonary Disease
Actual Study Start Date : March 20, 2024
Estimated Primary Completion Date : December 31, 2025
Estimated Study Completion Date : December 31, 2025

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 55 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion Criteria
  • 1. Age under 55, regardless of gender
  • 2. Patients with COPD lung disease who are going to undergo bronchoscopic biopsy
  • 3. No genetic diseases and other respiratory diseases
Exclusion Criteria
  • Other conditions determined by the investigators to be unsuitable for inclusion, such as difficult sampling, difficult follow-up, and complicated with other serious diseases
Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD

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Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD

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