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NCT06229860 | RECRUITING | Chronic Myeloid Leukemia


Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts W/Chronic Myeloid Leukemia
Sponsor:

University of California, Irvine

Information provided by (Responsible Party):

Mahtab Jafri

Brief Summary:

This is an observational pilot study to examine the association between a patient's personality and adherence to tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia.

Condition or disease

Chronic Myeloid Leukemia

Chronic Phase Chronic Myelogenous Leukemia

Intervention/treatment

Interview

Detailed Description:

The purpose of this pilot study is to explore the association between personality and adherence to a specific type of oral cancer medication - tyrosine kinase inhibitor (TKI) - in patients with chronic myeloid leukemia (CML). 75 individuals with chronic phase CML who are being treated with TKIs will be recruited. Consenting patients will participate in a focused interview where TKI adherence, personality type, and quality of life and symptom burden will be assessed using validated questionnaires. Information on treatment response and the treating physician's perception of TKI adherence will be obtained from the electronic health record.

Study Type : OBSERVATIONAL
Estimated Enrollment : 75 participants
Official Title : Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Patients with Chronic Myeloid Leukemia
Actual Study Start Date : 2024-01-25
Estimated Primary Completion Date : 2025-12-31
Estimated Study Completion Date : 2026-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * 18 years of age or older
  • * Diagnosed with chronic myeloid leukemia (CML) and in the chronic phase (CML-CP)
  • * Currently being treated with one of four cancer medications - imatinib, dasatinib, bosutinib, or nilotinib
  • * A patient at the UCI Chao Family Comprehensive Cancer Center (CFCCC), or
  • * A member of a patient support group organized by the CML Buster Foundation
  • * Do not meet any of the criteria listed under "Exclusion Requirements"
Exclusion Criteria
  • * Unable to read and speak English
  • * Impaired decisional capacity to consent

Impact of Personality on Adherence to Tyrosine Kinase Inhibitor Therapy in Pts W/Chronic Myeloid Leukemia

Location Details

NCT06229860


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Locations


RECRUITING

United States, California

Chao Family Comprehensive Cancer Center University of California, Irvine

Orange, California, United States, 92868

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