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NCT06159140 | RECRUITING | Small Vessel Disease


Small Vessel Diseases: Ultra-realistic Microstructure Computational Model to Refine Individual Treatment
Sponsor:

University Hospital, Tours

Brief Summary:

Small vessel disease (SVD) accounts for 25% of strokes and is the second most common cause of dementia after Alzheimer's disease. Unlike other causes of stroke, SVD manifests itself years before the stroke by the accumulation of tissue damage. Although heterogeneous, these lesions appear on Magnetic Resonance Imaging (MRI) as white matter hypersignals (WMH). In this context, the ANR SUMMIT project will characterize these lesions in vivo to develop new markers in the early stages of stroke. It is subdivided into 4 work packages, the third one being promoted by CHRU de Tours.

Condition or disease

Small Vessel Disease

Intervention/treatment

MRI

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 20 participants
Masking : NONE
Primary Purpose : DIAGNOSTIC
Official Title : Small Vessel Diseases: Ultra-realistic Microstructure Computational Model to Refine Individual Treatment
Actual Study Start Date : 2024-03-26
Estimated Primary Completion Date : 2026-03
Estimated Study Completion Date : 2026-03

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 82 Years to 100 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • Prior Enrollement in Tours body donation program Age ≥ 82 years Able to remain supine in the MR scanner for acquisition (duration 60-minutes) Affiliation to social security Informed and written consent
Exclusion Criteria
  • Contraindications to body donation, especially infectious disease (VIH, HBV...) Contraindications to MRI

Small Vessel Diseases: Ultra-realistic Microstructure Computational Model to Refine Individual Treatment

Location Details

NCT06159140


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How to Participate

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Locations


RECRUITING

France,

UHT of Tours

Tours, France,

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