Thinking of joining a study?

Register your interest

Become a volunteer?

NCT06152081 | RECRUITING | Caries,Dental

Caries Detection With Two Different Caries Detecting Devices
Sponsor:

Tufts University

Brief Summary:

The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression. The secondary aim is to compare the progression of carious lesions between patients who reported use of e-cigarettes/vapes and those who did not.

Condition or disease

Caries,Dental

Intervention/treatment

LumiCare rinse

QLF Inspektor Pro Imaging

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 60 participants
Masking : NONE
Primary Purpose : DIAGNOSTIC
Official Title : A Pilot Clinical Trial Comparing the Efficacy of Caries Detection With a Novel Caries Detecting Rinse and Existing Diagnostic Tools
Actual Study Start Date : 2025-04
Estimated Primary Completion Date : 2026-04
Estimated Study Completion Date : 2027-10

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 21 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Patients of TUSDM Comprehensive Care Clinic
  • * Adult patients over the age of 21
  • * Extreme/High Caries Risk classification per TUSDM Caries Management by Risk Assessment (CAMBRA) form
  • * Presence of 2 or more initial active primary carious lesions on a free coronal surface of any tooth by visual assessment, QLF, and LumiCare™
  • * Presence of at least 1 cavitated lesion
  • * Updated (no more than 6 months old) bite wing radiographs available.
  • * Patients who responded either yes/no to use of e-cigarettes/vapes
  • * 1 active caries, 1 inactive caries and 1 sound tooth surface.
Exclusion Criteria
  • * Low or moderate caries risk classification per TUSDM CAMBRA form
  • * No clinically detectable carious lesions on free coronal surfaces
  • * No cavitated caries lesions
  • * Carious teeth with caries lesions concomitant with extrinsic stains, fluorosis, or developmental defects.
  • * Patients who responded yes to the use of conventional cigarettes or smokeless tobacco
Caries Detection With Two Different Caries Detecting Devices

Location Details

NCT06152081

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Massachusetts

Tufts University School of Dental Medicine

Boston, Massachusetts, United States, 02111