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NCT06151158 | RECRUITING | Suicide, Attempted


Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
Sponsor:

Johns Hopkins University

Brief Summary:

The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps people prevent suicidal crises from escalating, and Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI), a psychotherapeutic crisis intervention treatment for suicidal adolescents that teaches youth skills to prevent suicidal crises and addresses interpersonal problems that lead to suicidal crises. The results will inform the future standard of care for youth at risk for suicide presenting in the ED setting. This project focuses on suicidal youth ages 12-19 in three ethnically and racially diverse urban areas: Philadelphia, Pennsylvania; Baltimore, Maryland; and upper Manhattan/lower Bronx in New York City.

Condition or disease

Suicide, Attempted

Suicide Ideation

Suicide

Suicide Prevention

Intervention/treatment

Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+)

Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI)

Phase

NA

Detailed Description:

Emergency department (ED) visits for suicide-related concerns have been increasing in youth over the past decade, a trend potentially exacerbated by the COVID-19 pandemic. Also, youth suicidal thoughts and attempts have increased with the 2019 Centers for Disease Control and Prevention (CDC) Youth Risk Behavior Surveillance System (YRBSS) finding that 18.8 percent of high school students have seriously considered suicide and 8.9 percent had attempted suicide in the past year. Furthermore, suicide rates are increasing more rapidly in Latino/Latina, Black, and multiracial youth, especially Black youth as compared to White youth. Similar increases in suicide risk are seen in lesbian, gay, bisexual, transgender, queer and other sexually minority (LGBTQ+) youth. This project focuses on suicidal youth ages 12-19 in three ethnically and racially diverse urban areas: Philadelphia, Pennsylvania; Baltimore, Maryland; and upper Manhattan/lower Bronx in New York City. There is limited evidence about which interventions are most helpful for suicidal youth in acute care settings such as EDs. Interventions like safety planning (Safety Planning Intervention with follow-up contacts) are delivered primarily in ED settings while others like Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI) are provided primarily in outpatient settings. Furthermore, safety planning focuses on deescalating suicidal crises when beginning to occur, while IPT-A SCI focuses on developing skills to prevent crises from occurring. While both approaches have an evidence base, it is not yet known which one is more effective and acceptable in a diverse youth population. Determining which intervention is more effective has implications for dissemination and resource allocation to EDs or outpatient settings. The research team includes a group of ethnically and racially diverse partners and advisors, advocates, researchers, ED physicians, nurses, and social workers, some of whom have lived experience of suicide attempts and suicide loss. This team has provided feedback about crucial elements of this proposal, e.g., recruitment, intervention approaches, and follow-up approaches and will continue active involvement in all stages of this project. The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the SPI+, a suicide-specific intervention that helps people prevent suicidal crises from escalating, and IPT-A SCI, a psychotherapeutic crisis intervention treatment for suicidal adolescents that teaches youth skills to prevent suicidal crises and addresses interpersonal problems that lead to suicidal crises. The results will inform the future standard of care for youth at risk for suicide presenting in the ED setting.

Study Type : INTERVENTIONAL
Estimated Enrollment : 1000 participants
Masking : SINGLE
Primary Purpose : PREVENTION
Official Title : Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
Actual Study Start Date : 2025-03-10
Estimated Primary Completion Date : 2028-10-14
Estimated Study Completion Date : 2028-10-14

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 12 Years to 19 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Acute care visit for suicide-related concern or screen positive on a suicide risk screener (serious SI as indicated by a C-SSRS screening endorsing question two "Have you actually had any thoughts of killing yourself?" in past four weeks or SA in past four weeks);
  • * Has a cell phone with ability to receive phone calls and text messages over the 12-month follow-up;
  • * Ability to speak, understand, and read in English or Spanish
Exclusion Criteria
  • * Significant cognitive or developmental delays that prevent understanding or using SPI or IPT-A SCI. Participants must be verbally fluent and have the ability to communicate verbally. This will, in part, be determined by notes in Epic and/or by asking one of the patient's parents/clinicians;
  • * Altered mental status that precludes ability to provide informed assent or consent (acute psychosis, intoxication, or mania);
  • * Unable to provide informed consent (adults); assent (minors); permission (parents/caregivers).

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Location Details

NCT06151158


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Locations


NOT YET RECRUITING

United States, Florida

Johns Hopkins All Children's Hospital

Saint Petersburg, Florida, United States, 33701

RECRUITING

United States, Maryland

Johns Hopkins University

Baltimore, Maryland, United States, 21205

NOT YET RECRUITING

United States, New York

Columbia University Irving Medical Center (CUMC)

New York, New York, United States, 10032

NOT YET RECRUITING

United States, New York

Weill-Cornell Medicine

New York, New York, United States, 10065

NOT YET RECRUITING

United States, North Carolina

University of North Carolina Medical Center

Chapel Hill, North Carolina, United States, 27514

NOT YET RECRUITING

United States, Pennsylvania

Childrens Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

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