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NCT06149078 | NOT YET RECRUITING | Knee Osteoarthritis


The Relationship of Serum Uric Acid With Severity of Knee Osteoarthritis
Sponsor:

Sohag University

Information provided by (Responsible Party):

Aya Mohamed know

Brief Summary:

Osteoarthritis (OA) is the most prevalent form of arthritis. Its pathogenesis remains poorly understood. Though historically regarded as a disease of mechanical degeneration, it is now appreciated that inflammation plays an important role in OA pathogenesis (Krasnokutsky et al., 2017). The hallmark of OA is the degradation and loss of articular cartilage, although most tissues of the joint become affected, such as bone, synovium, ligaments, menisci (knee), labrum (hip), periarticular fat, and muscle (Englund, 2023).It is believed that there is a pathological link between hyperuricemia and OA Therefore, we conducted a cross-sectional study to evaluate an association between elevated SUA and radiographic OA of the knee) Bipan Shrestha, 2019 (.

Condition or disease

Knee Osteoarthritis

Intervention/treatment

serum uric acid

Study Type : OBSERVATIONAL
Estimated Enrollment : 150 participants
Official Title : The Relationship of Serum Uric Acid With Severity of Knee Osteoarthritis
Actual Study Start Date : 2023-12-10
Estimated Primary Completion Date : 2024-05-10
Estimated Study Completion Date : 2024-05-10

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Adult patient (Age\>18 years) with a complaint of knee pain.
Exclusion Criteria
  • * 1.Any patient with a history of trauma to the knee. 2 Any patient with knee complaints as a part of autoimmune connective tissue disease.

The Relationship of Serum Uric Acid With Severity of Knee Osteoarthritis

Location Details

NCT06149078


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Locations


Not yet recruiting

Egypt,

Sohag University Hospital

Sohag, Egypt,

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