Erasme University Hospital
The goal of this prospective, interventionnal clinical trial is to assess if intravenous administration of linisol reduce the ED50 of propofol when administered using Target Controlled Infusion (TCI) during gastroscopy in healthy patients (ASA 1 and 2 patients). Prior to propofol sedation, participants will receive either an intravenous bolus of linisol (1.5 mg/kg) = treated group or placebo = control group.
Diagnostic Gastroscopy
Lidocaine 2% Injectable Solution
Saline administration as placebo
Propofol injection
gastroscopy
NA
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 50 participants |
| Masking : | QUADRUPLE |
| Masking Description : | computered randomisation, sealed enveloppes linisol versus placebo prepared by anesthesist not involved in the study or in patient care |
| Primary Purpose : | SUPPORTIVE_CARE |
| Official Title : | Does Intravenous Lidocaine Reduce ED 50 for Propofol Administered Using Target Controlled Infusion (TCI) During Gastroscopy in ASA 1 and 2 Patients. |
| Actual Study Start Date : | 2024-04-08 |
| Estimated Primary Completion Date : | 2024-08-31 |
| Estimated Study Completion Date : | 2024-08-31 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years to 65 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
BOUDART Céline
Bruxelles, Belgium, 1070