The University of Texas Health Science Center at San Antonio
Gustavo Almeida
The aim is to demonstrate that preoperative exercises (prehabilitation) using blood-flow restriction training (BFRT) is safe, well tolerated, improves muscle function, decreases functional limitation, and increases physical activity in older adults awaiting total knee replacement (TKR).
Knee Osteoarthritis
Blood Flow Restriction Training (BFRT)
NA
Twenty individuals ≥60 years old awaiting TKR due to diagnosis of end-stage knee osteoarthritis who meet the inclusion/exclusion criteria will be invited to participate in a 6 weeks of low-intensity BFRT prehabilitation. We will assess muscle functional (i.e., cross-sectional area and intramuscular fatty content) using computerized tomography, quadriceps muscle strength using an isokinetic dynamometer, a battery of performance-based physical function, self-reported physical function and quality of life, and biomarkers of inflammation using blood serum. Feasibility assessment will be done by looking at safety (i.e., adverse events), compliance, and attrition rate.
Study Type : | INTERVENTIONAL |
Estimated Enrollment : | 20 participants |
Masking : | NONE |
Primary Purpose : | PREVENTION |
Official Title : | Feasibility of Prehabilitation Blood-flow Restriction Training in Individuals Awaiting Total Knee Replacement. |
Actual Study Start Date : | 2022-09-23 |
Estimated Primary Completion Date : | 2024-12 |
Estimated Study Completion Date : | 2024-12 |
Information not available for Arms and Intervention/treatment
Ages Eligible for Study: | 60 Years |
Sexes Eligible for Study: | ALL |
Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
UT Health San Antonio- Dept. of Physical Therapy
Saint Anthony, Texas, United States, 78229