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NCT05943834 | RECRUITING | Neurocognitive Disorders

Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis (PLATA)
Sponsor:

Nice University Hospital Center

Brief Summary:

PLATA aims to develop an algorithm to identify vocal biomarkers of Alzheimer's dementia. Using data collected as part of routine care, speech patterns will be compared to known biomarkers of Alzheimer's disease, such as amyloid 1-42 and p-Tau in CSF (cerebrospinal fluid). If biomarkers of speech can be identified in Alzheimer's disease, it is possible that patients and research participants will no longer need to undergo need to undergo the intensive and invasive baseline biomarker methods currently used, such as lumbar punctures and PET scans.

Condition or disease

Neurocognitive Disorders

Intervention/treatment

Series of cognitive tasks during a semi-automated call

Study Type : OBSERVATIONAL
Estimated Enrollment : 100 participants
Official Title : Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis
Actual Study Start Date : 2023-07-13
Estimated Primary Completion Date : 2027-10-10
Estimated Study Completion Date : 2027-10-10

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 50 Years to 100 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Age ≥ 50 years
  • * Diagnosis relevant biomarker and neuropsychological data already available
  • * Cognitively healthy to very mild dementia (CDR score max. 0.5)
  • * Sufficient knowledge of the study language to understand study information, non opposition form,and questionnaires
  • * Expression of non opposition
Exclusion Criteria
  • * Hearing problems
  • * Patient protected by law, under guardianship or curator ship, or not able to participate in a clinical study according to the article L.1121-16 of the French Public Health Code
Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis (PLATA)

Location Details

NCT05943834

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How to Participate

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Locations

RECRUITING

France,

chu's nice

Nice, France, 06100