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NCT05898594 | RECRUITING | Lung Cancer

Lung Cancer Screening in High-risk Black Women
Sponsor:

Massachusetts General Hospital

Information provided by (Responsible Party):

Chi-Fu Jeffrey Yang

Brief Summary:

The goal of this research study is to study U.S. Black women with a history of smoking to examine the feasibility, acceptability, and performance of low-dose computed tomography (LDCT) screening among this population. The name of the intervention used in this research study is: Low-dose computed tomography (radiologic scan) chest scan

Condition or disease

Lung Cancer

Lung Carcinoma

Intervention/treatment

Low-dose Computed Tomography

Phase

NA

Detailed Description:

The goal of this single-arm pilot research study is to evaluate the feasibility and acceptability of low-dose computed tomography (LDCT) screening for lung cancer among U.S. Black women with a history of smoking. LDCT screening is currently the only recommended way to screen for lung cancer among high-risk individuals. However, the majority of Black women at high-risk for lunch cancer are currently ineligible for lung cancer screening. Study procedures include screening for eligibility, completion of questionnaires, and a LDCT screening test. Participation in this study is expected to last up to 3 months. It is expected about 900 people will participate in this study.

Study Type : INTERVENTIONAL
Estimated Enrollment : 900 participants
Masking : NONE
Primary Purpose : SCREENING
Official Title : Evaluating the Feasibility of Lung Cancer Screening in High-risk Black Women
Actual Study Start Date : 2023-09-06
Estimated Primary Completion Date : 2028-06-30
Estimated Study Completion Date : 2028-06-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Self-identified Black women.
  • * Have a self-reported history of smoking. No restriction will be placed on the number of smoking pack years participants must have nor the number of years former smokers must have quit smoking.
  • * Aged \>= 50 years.
Exclusion Criteria
  • * Individuals with a history of lung cancer.
  • * Individuals with symptoms suggestive of lung cancer. We will evaluate whether women have symptoms suggestive of lung cancer by administering an online screening questionnaire, which will ask whether they have experienced shortness of breath, whether they become easily winded, and whether they have had a chronic cough within the last 12 weeks that has not improved. Women who select that they have any one of these symptoms will be advised to follow up with their primary doctor and will not be eligible to participate in the study.
  • * Individuals with pneumonia or acute respiratory infection within 12 weeks prior to enrollment that was treated with antibiotics.
Lung Cancer Screening in High-risk Black Women

Location Details

NCT05898594

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Illinois

University of Chicago

Chicago, Illinois, United States, 60637

RECRUITING

United States, Massachusetts

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States, 02215