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NCT05878665 | Not yet recruiting | Appendicitis Acute


Low-dose Contrast Media for Low-kVp Abdomen CT
Sponsor:

Bohyun Kim

Information provided by (Responsible Party):

Bohyun Kim

Brief Summary:

The purpose of this clinical study is to test the performance of low radiation dose abdominal CT combined with low dose contrast media for the diagnosis of acute appendicitis in young patients. The main questions to be answered are: 1, Can low-dose contrast media paired with low-dose radiation CT of the abdomen provide acceptable diagnostic accuracy in acute appendicitis? 2. How much radiation dose can be saved by using low radiation dose abdominal CT in combination with low dose contrast media?

Condition or disease

Appendicitis Acute

Intervention/treatment

Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT

Phase

Not Applicable

Study Type : Interventional
Estimated Enrollment : 292 participants
Masking : None (Open Label)
Primary Purpose : Diagnostic
Official Title : Optimizing Low-dose Contrast Media Protocol for Low-kVp Abdominopelvic CT in Suspected Acute Appendicitis
Actual Study Start Date : November 30, 2023
Estimated Primary Completion Date : April 15, 2024
Estimated Study Completion Date : December 31, 2024
Arm Intervention/treatment

Experimental: Double low-dose CT

Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT

Diagnostic Test: Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT

Ages Eligible for Study: 19 Years to 44 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion criteria
  • Patients in the emergency department with suspected acute appendicitis based on clinical examination
  • Patients scheduled for contrast-enhanced CT of the abdomen and pelvis for diagnosis of suspected acute appendicitis.
  • Exclusion criteria
    • Patients who decline to participate
    • Contraindications to contrast-enhanced CT (eGFR < 30 mL/min/173 m^2 or pregnant)
    • BMI >= 30.

Low-dose Contrast Media for Low-kVp Abdomen CT

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Low-dose Contrast Media for Low-kVp Abdomen CT

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