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NCT05877261 | Recruiting | Knee Arthroplasty, Total


Cementless Triathlon 5YR Follow-Up
Sponsor:

Lawson Health Research Institute

Information provided by (Responsible Party):

Brent Lanting

Brief Summary:

All artificial joint implants need to be solidly held (fixed) within the bone. Cementless fixation has become a popular method to achieve fixation for total knee replacements where the bone grows directly onto the implanted device instead of using bone cement. The primary purpose of this study is to assess long-term implant survivorship and clinical outcomes of a previous study cohort that received a cementless knee replacement. As this study cohort approaches 5 years post-operation, the investigators will re-examine the stability of participant implants using specialized x-rays, called "radiostereometric analysis". The study will use weight-bearing computed tomography (CT) to measure bone density and texture features and correlate that with implant stability. The investigators will collect stool samples to assess participant gut microbiomes for biomarkers of poor bone quality that could correlate to implant stability. All 33 participants from the original study cohort will be invited to participate in this study.

Condition or disease

Knee Arthroplasty, Total

Knee Osteoarthritis

Radiostereometric Analysis

Intervention/treatment

Cementless Total Knee Replacement

Study Type : Observational
Estimated Enrollment : 33 participants
Official Title : 5 Year Follow-Up of Migration of a Cementless Total Knee Replacement
Actual Study Start Date : May 25, 2023
Estimated Primary Completion Date : March 2024
Estimated Study Completion Date : June 2024

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 21 Years to 90 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion Criteria
  • Were in the originally investigated cohort
  • Had successful imaging at 1-year post-operation
  • Minimum of 5 years post-operation
Exclusion Criteria
  • Pregnancy
  • Unable to follow-up

Cementless Triathlon 5YR Follow-Up

Location Details


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Cementless Triathlon 5YR Follow-Up

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


Recruiting

Canada, Ontario

University Hospital

London, Ontario, Canada, We get bored

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