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NCT05875285 | UNKNOWN | Hyperhidrosis

Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis
Sponsor:

Cairo University

Information provided by (Responsible Party):

Nayera Radwan Fathy

Brief Summary:

The purpose of the study is to compare the therapeutic effect of methotrexate iontophoresis versus coal tar ointment on the the treatment of primary palmer hyperhidrosis?

Condition or disease

Hyperhidrosis

Iontophore

Intervention/treatment

Iontophoresis with methotrexate

Iontophoresis with coal tar ointement

Phase

NA

Detailed Description:

Some researchers stated that hyperhidrosis can render the skin susceptible to infection because of the continuous dampness of the skin. The condition may become socially, psychologically and professionally debilitating. There are a lot of literatures concerned with studying the modalities used in the treatment of primary palmar hyperhidrosis, so this study will be conducted to compare between two of them and to show the best one for treating primary palmar hyperhidrosis.

Study Type : INTERVENTIONAL
Estimated Enrollment : 60 participants
Masking : DOUBLE
Primary Purpose : TREATMENT
Official Title : Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis
Actual Study Start Date : 2023-06-01
Estimated Primary Completion Date : 2023-08-20
Estimated Study Completion Date : 2023-10-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 15 Years to 35 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Patient with primary palmar hyperhidrosis to extend that their palms are wet during most of the day (score 3 and 4 in the Hyperhidrosis Disease Severity Scale) was included in this study.
  • * The palmer hyperhidrosis patient's age ranged from 15 to 35 years.
  • * All patients will be examined by dermatologist before starting the study.
Exclusion Criteria
  • The study excluded the following patients
    • * Patients with medical conditions that associated with hyperhidrosis are excluded, these conditions include:- hyperthyroidism, diabetes mellitus, parkinsonism, spinal cord injury, brain damage, congestive heart failure, anxiety, alcoholism and menopause.
    • * Patients who received any treatment with a drug that was affecting sweating e.g. (thyroxin, anxiolytics.....) that is not stopped at least 4 weeks preceding the study.
    • * Patients with cardiac conditions such as arrhythmia, ischemic heart disease, low exercise tolerance, low respiratory reserve were excluded.
    • * Patients, who have a local wound, sever eczema and severe fungal infection of the palms to minimize risk of local burn.
    • * Patients who have sensory disorders.
    • * Female patients who are pregnant and lactating.
Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis

Location Details

NCT05875285

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Locations

Not yet recruiting

Egypt,

Outpatient clinic faculty of physical therapy cairo university

Cairo, Egypt,