Chulalongkorn University
Pornanong Aramwit, Pharm.D., Ph.D
The object of this study was to evaluate safety of cream containing sericin and turmeric in healthy volunteers.
Safety Issues
cream containing 2.5% sericin and 2%turmeric
cream containing 5%sericin and 2%turmeric
cream containing 10%sericin and 2%turmeric
cream base
Not Applicable
There are 106 healthy volunteers in this study. Upper left arm is divided into 2 parts (2x2 cm) which are A and B area. Upper right arm is divided into 2 parts (2x2 cm) which are C and D area. Four area (A, B, C, and D) are randomized to receive cream containing 2.5% sericin and 2%turmeric, cream containing 5%sericin and 2%turmeric, cream containing 10%sericin and 2%turmeric, and cream base (Control group). Samples are applied 2 times/day for 6 days (Induction phase). Then, the volunteers will stop applying samples for 7 to 10 days (Free period). After that, Samples are applied 2 times/day for 3 days (Challenge phase). Erythema, melanin, humidity, transepidermal water loss, skin adverse reaction, and satisfaction are evaluated.
Study Type : | Interventional |
Estimated Enrollment : | 106 participants |
Masking: | Triple |
Primary Purpose: | Other |
Official Title: | Safety of Cream Containing Sericin and Turmeric in Healthy Volunteers |
Actual Study Start Date : | July 1, 2023 |
Estimated Primary Completion Date : | October 30, 2023 |
Estimated Study Completion Date : | November 30, 2023 |
Arm | Intervention/treatment |
---|---|
Experimental: cream containing 2.5% sericin and 2%turmeric cream containing 2.5% sericin and 2%turmeric |
Other: cream containing 2.5% sericin and 2%turmeric |
Experimental: cream containing 5%sericin and 2%turmeric cream containing 5% sericin and 2%turmeric |
Other: cream containing 5%sericin and 2%turmeric |
Experimental: cream containing 10%sericin and 2%turmeric cream containing 10% sericin and 2%turmeric |
Other: cream containing 10%sericin and 2%turmeric |
Experimental: cream base cream base without sericin and tumeric |
Other: cream base |
Ages Eligible for Study: | 18 Years to 60 Years |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Accepts Healthy Volunteers |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Not yet recruiting
Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn Unviersity
Bangkok, Thailand, 10310