All India Institute of Medical Sciences, Bhubaneswar
Dr. Debatta Mohapatra
The goal of this Randomized Controlled Trial is to to compare the effect of Risperidone vs Aripiprazole in terms of change in serum Glutathione level in patients with Autism Spectrum Disorder over a period of 6 weeks. The main questions it aims to answer are: 1. (Primary Outcome) Change in serum Glutathione levels following 6 weeks of intervention in both the arms 2. (Secondary Outcomes) Change in serum superoxide dismutase (SOD) levels following 6 weeks of intervention. Change in ISAA score following 6 weeks of intervention. Change in ABC-C score following 6 weeks of intervention. • Adverse events reported in both groups Details of intervention- One arm of the study population to get Risperidone 1mg/day for a total duration of 6 weeks and another arm to get Aripiprazole 2mg/day for a total duration of 6 weeks. Baseline assessment of Serum Glutathione, Serum SOD, ISAA scale, ABC-C scale will be done and same will be assesssed at 6 weeks follow up.
The Goal of This Trial is to to Compare the Effect of Risperidone vs Aripiprazole in Terms of Change in Serum Glutathione Level
Risperidone, Aripiprazole
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| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 42 participants |
| Masking : | DOUBLE |
| Primary Purpose : | TREATMENT |
| Official Title : | EFFECT OF RISPERIDONE vs ARIPIPRAZOLE ON OXIDATIVE STRESS IN PATIENTS WITH AUTISM SPECTRUM DISORDER: A RANDOMIZED CONTROLLED TRIAL |
| Actual Study Start Date : | 2023-07-01 |
| Estimated Primary Completion Date : | 2024-05-02 |
| Estimated Study Completion Date : | 2025-03-02 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 5 Years to 18 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
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