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NCT05864898 | Not yet recruiting | Acute Respiratory Failure Patients on NIV and HFNC


Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula
Sponsor:

Assiut University

Information provided by (Responsible Party):

Hussein Makarem

Brief Summary:

Comparison between some predictors of failure of non-invasive ventilation and high flow nasal cannula.

Condition or disease

Acute Respiratory Failure Patients on NIV and HFNC

Detailed Description:

Delayed intubation after NIV / HFNC failure is associated with high mortality rate in acute respiratory failure patients. There are Many factors to predict early failure but World still searching for new factors and comparing between each ;in order to eatablish best one that achieve the least mortality rate. Little studies about effiecacy of HACOR Score as a predictor of failure in HFNC patients. Little studies about effiecacy of ROX Index as a predictor of failure in NIV ventilating patients.}}

Study Type : Observational
Estimated Enrollment : 120 participants
Official Title : Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula in Acute Respiratory Failure Patients : the Standardized PaO2 / FiO2 Ratio (P /F-st), ROX Index and HACOR
Actual Study Start Date : July 1, 2023
Estimated Primary Completion Date : April 1, 2024
Estimated Study Completion Date : July 1, 2024

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: All
Criteria
Inclusion Criteria
  • Acute respiratory failure patients who need ventilatory Support either NIV or HFNC due to
    • RR > 25 cycle / min
    • using accessory muscles and paradoxical breath.
    • PaO2 / FiO2 ratio < 300
    Exclusion Criteria
    • Absolute indication for intubation like coma, haemodynamically unstable… etc
    • Contr-indication of NIV like untreated Pneumothorax.

Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula

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Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula

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