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NCT05864794 | RECRUITING | Non Small Cell Lung Cancer Metastatic

Value of Screening MRI Brain in Stage IV Non-small Cell Lung Cancer
Sponsor:

University Medical Center Groningen

Brief Summary:

Patients with newly diagnosed stage IV non-oncogene addicted NSCLC, who are fit for systemic treatment and don't have any symptoms of brain disease will undergo an MRI of the brain to screen for brain disease.

Condition or disease

Non Small Cell Lung Cancer Metastatic

Intervention/treatment

MRI

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 100 participants
Masking : NONE
Primary Purpose : SCREENING
Official Title : ValUe of Screening MRI Brain in Patients With Newly Diagnosed Stage IV Non-oncogene Addicted Non-small Cell Lung CANcer - The VULCAN Trial
Actual Study Start Date : 2024-05-13
Estimated Primary Completion Date : 2025-09-01
Estimated Study Completion Date : 2026-07-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Histologically or cytologically confirmed stage IV metastatic NSCLC, not amenable to curative treatment.
  • * Fit for systemic treatment (PS 0-2) according to standard of care.
  • * No symptoms of brain disease disease assessed according to standard clinical care by the thoracic oncologist.
Exclusion Criteria
  • * Prior/concomitant therapy for stage IV disease.
  • * Oncogenic diver mutation (e.g. EGFR, ALK, ROS1, RET, MET, and BRAF) with approved targeted treatment.
  • * Contraindications for MRI scan with contrast as per standard of care protocol of the institution.
Value of Screening MRI Brain in Stage IV Non-small Cell Lung Cancer

Location Details

NCT05864794

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

Netherlands,

University Medical Center Groningen

Groningen, Netherlands, 9713 Laz