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NCT05864521 | RECRUITING | Healthy

Beetroot Juice and Sleep
Sponsor:

Mayo Clinic

Information provided by (Responsible Party):

Virend Somers, MD, PhD

Brief Summary:

The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.

Condition or disease

Healthy

Intervention/treatment

Active Beetroot Juice Supplement (aBRJ)

Placebo Beetroot Juice Supplement (pBRJ)

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 60 participants
Masking : DOUBLE
Primary Purpose : BASIC_SCIENCE
Official Title : Effects of Nocturnal Inorganic Nitrate Supplementation on Physiological Function
Actual Study Start Date : 2023-09-28
Estimated Primary Completion Date : 2026-06
Estimated Study Completion Date : 2026-06

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 80 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * 18-35 or 65-80 years of age
Exclusion Criteria
  • * Coronary artery disease
  • * Heart failure
  • * Pregnancy
  • * Diabetes
  • * Sleep disorders
  • * Shift workers
  • * Individuals who typically go to sleep after midnight
  • * Individuals who traveled across ≥2 time zones within one week of study visits
  • * Individuals with a history frequent kidney stones
  • * BMI ≥35.0kg/m2
  • * Use of nicotine-containing products within the two years preceding study visits
  • * Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with the nitrate-nitrite-nitric oxide pathway or outcome measures
Beetroot Juice and Sleep

Location Details

NCT05864521

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Minnesota

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905