Thinking of joining a study?

Register your interest

Become a volunteer?

NCT05839535 | RECRUITING | Knee Osteoarthritis

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA
Sponsor:

Massachusetts General Hospital

Information provided by (Responsible Party):

J Ian Kong

Brief Summary:

This study will combine brain imaging and neuromodulation tools to investigate the underlying neurobiological mechanisms of exercises. The findings will enhance our understanding of the mechanisms underlying mind-body exercise and facilitate the development of new pain management approaches.

Condition or disease

Knee Osteoarthritis

Intervention/treatment

BDJ

tDCS

sham tDCS

exercise

Phase

PHASE2

Study Type : INTERVENTIONAL
Estimated Enrollment : 140 participants
Masking : DOUBLE
Primary Purpose : OTHER
Official Title : Enhancing Modulation Effects of Baduanjin Through Non-invasive Neuromodulation for Knee Osteoarthritis
Actual Study Start Date : 2024-03-05
Estimated Primary Completion Date : 2028-03-30
Estimated Study Completion Date : 2028-08-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 45 Years to 75 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Volunteers 45-75 years of age
  • * Meet the Classification Criteria of the American College of Rheumatology for osteoarthritis of the right and/or left knee for at least the past 3 months;
  • * Physically able to participate in the BDJ and stretching control education programs
  • * Willing to complete the 12-week study
  • * Can participate in MRI scan
  • * Ability to read and understand English; English can be a second language provided that the patient feels he or she can understand all the questions used in the assessment measures
Exclusion Criteria
  • * Has performed BDJ, Tai Chi, Yoga, other mind-body intervention, physical therapy, or routine exercise (running, cycling, etc.) regularly in the past year
  • * Serious medical conditions limiting ability of patient to participate in the study, such as symptomatic cardiovascular disease, symptomatic pulmonary disease requiring supplemental oxygen, uncontrolled metabolic diseases, severe renal and liver disease
  • * Has had intra-articular steroid injections or reconstructive surgery in the prior 3 months on the affected knee; any intra-articular hyaluronic acid injections in the previous 6 months
  • * Patient Mini-Mental Status Examination score below 24 \[293\]
  • * Unable to walk without a cane or other assistive device
  • * The intent to undergo surgery during the time of involvement in the study
  • * Plan to permanently relocate from the region during the trial period
Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

Location Details

NCT05839535

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, Massachusetts

Massachusetts General Hospital

Charlestown, Massachusetts, United States, 02129