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NCT05788016 | RECRUITING | Arthritis Knee


Developing an Opioid Taper Intervention Before Total Joint Arthroplasty
Sponsor:

University of Alabama at Birmingham

Information provided by (Responsible Party):

Kevin Riggs

Brief Summary:

The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are: * Is the intervention feasible and acceptable to patients? * Does the intervention result in a decrease in opioid dose during the preoperative period? Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.

Condition or disease

Arthritis Knee

Arthritis Hip

Chronic Pain

Intervention/treatment

opioid taper

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 45 participants
Masking : NONE
Primary Purpose : SUPPORTIVE_CARE
Official Title : Developing and Testing an Opioid Taper Intervention Before Total Knee Arthroplasty: Phase 2 Intervention Development
Actual Study Start Date : 2024-01-10
Estimated Primary Completion Date : 2025-03-03
Estimated Study Completion Date : 2025-03-03

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * decided to pursue primary, unilateral total knee or hip arthroplasty with planned surgery date in 4-8 weeks
  • * currently taking between 20 and 90 MME of oral opioids, and that dose has been stable for at least 3 months
  • * have a reliable telephone number for contact
  • * speaks English
Exclusion Criteria
  • * Taking opioid medications that include
    • * Buprenorphine
    • * Methadone
    • * Long-acting formulations of opioid pain medications (e.g., extended-release oxycodone and extended-release morphine)
    • * Transdermal formations of opioid pain medications (e.g., fentanyl patches)

Developing an Opioid Taper Intervention Before Total Joint Arthroplasty

Location Details

NCT05788016


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Locations


RECRUITING

United States, Alabama

UAB Hospital-Highlands

Birmingham, Alabama, United States, 35205

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