Thinking of joining a study?

Register your interest

NCT05734430 | RECRUITING | Appendix Cancer


Genetics of Appendix Cancer Study
Sponsor:

Andreana Holowyj, PhD, MSCI

Information provided by (Responsible Party):

Andreana Holowyj, PhD, MSCI

Brief Summary:

The GAP Study is a prospective cohort study designed to comprehensively investigate genetic variations that may contribute to cancer development among individuals diagnosed with appendix/appendiceal cancer who are ages 18+ years.

Condition or disease

Appendix Cancer

Appendiceal Cancer

Appendiceal Neoplasms

Appendiceal Mucinous Neoplasm

Appendiceal Adenocarcinoma

Appendiceal Carcinoid Tumor

Appendiceal Neoplasm Malignant Secondary

Appendix Adenocarcinoma

Appendix Mucinous Neoplasm

Appendix Tumor

Appendix Cancer Metastatic

Appendix NET

Low-Grade Appendix Mucinous Neoplasm

High Grade Appendix Mucinous Neoplasm

High Grade Appendix Mucinous Adenocarcinoma

Intervention/treatment

Genetic profiling

Retrospective tissue procurement

Detailed Description:

The Genetics of Appendix Cancer (GAP) Study aims to analyze hereditary factors, tumor characteristics and clinical features/outcomes among adults diagnosed with appendix cancer and their biological parents. Patients are recruited at any time after a diagnosis of appendix cancer and followed for up to 6 years after study enrollment. This cohort is enriched by robust biospecimens and data collections.

Study Type : OBSERVATIONAL
Estimated Enrollment : 700 participants
Official Title : Genetics of Appendix Cancer: The GAP Study
Actual Study Start Date : 2022-11-11
Estimated Primary Completion Date : 2032-11
Estimated Study Completion Date : 2034-11

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • GAP Social
  • * Known diagnosis of appendix cancer in the United States
  • * Mentally and physically able to consent and participate in the study
  • GAP Vanderbilt
  • * Known diagnosis of appendix cancer
  • * Diagnosed by and/or consulting with a physician/clinical provider participating in the GAP Study
  • * Mentally and physically able to consent and participate in the study
  • GAP Parent
  • * Biological parents (mother and/or father) of individuals actively participating in the GAP Study
  • * Residing in the United States
  • * Mentally and physically able to consent and participate in the study
Exclusion Criteria
  • * Women pregnant at the time of consent
  • * Prisoners
  • * Unable to provide informed consent
  • * Unable to read, write, or complete questionnaires in English

Genetics of Appendix Cancer Study

Location Details

NCT05734430


Please Choose a site



How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


RECRUITING

United States, Tennessee

Vanderbilt-Ingram Cancer Center

Nashville, Tennessee, United States, 37232

Loading...