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NCT05712759 | Not yet recruiting | Infection Viral


Nosocomial Influenza Surveillance of 2022 - 2027 Seasonal Period
Sponsor:

Civil Hospices of Lyon

Brief Summary:

Hospital-Acquired Influenza (HAI) is closely linked to the intensity of influenza in the community. HAI is associated with significant morbidity, mortality and extra costs due to prolonged hospital stay. The incidence of laboratory confirmed HAI has been reported rarely. The proportion of HAI among influenza cases was 11.38% (95% Confidence Interval: 5.19%-19.55%) in a meta-analysis of 14 studies. In France, a prospective surveillance study of adults with Influenza-Like Illness (ILI) over 11 years, reported that 35.6% of the influenza cases diagnosed at hospital were hospital-acquired. HAI is transmitted via respiratory droplets and by hand contacts. The spread is facilitated by Health Care Professionals (HCPs), patients and visitors. Prevention and control of HAI is of upmost importance to preserve patient safety and limit the related economic costs. While vaccination of HCPs has been shown to contribute to the reduction of HAI, less is known on the impact of patient vaccination on the risk of HAI during hospitalization. The aim of this study is to describe the hospital-acquired influenza in a french university hospital.

Condition or disease

Infection Viral

Intervention/treatment

Influenza-like illness group

Study Type : Observational
Estimated Enrollment : 350 participants
Official Title : Surveillance of Nosocomial Influenza at Edouard Herriot University Hospital, Lyon, France
Actual Study Start Date : February 1, 2025
Estimated Primary Completion Date : June 1, 2028
Estimated Study Completion Date : June 1, 2028

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion Criteria
  • Any volunteer adult patient (≥ 18 years of age) hospitalized for at least 24 hours on a study unit, who had a nasopharyngeal swab taken as part of care for the purpose of diagnosing influenza by PCR testing and who had an influenza-like illness meeting the following definition:
  • Fever greater than 37.8°C in the absence of antipyretics; And/or
  • Cough or pharyngeal pain.
Exclusion Criteria
  • Any person who does not meet the above definition or who has expressed opposition.

Nosocomial Influenza Surveillance of 2022 - 2027 Seasonal Period

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Nosocomial Influenza Surveillance of 2022 - 2027 Seasonal Period

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