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NCT05706545 | Not yet recruiting | Cardiac Surgery


Micro- and Macro-Circulation in Cardiac Surgery Patients
Sponsor:

IRCCS Policlinico S. Donato

Information provided by (Responsible Party):

Power Barry

Brief Summary:

The hypothesis under the study is that there could be a link between a dysfunction in peripheral microcirculation, sublingual microcirculation or cardiovascular control and the development of post cardiac surgery major morbidities (stroke, acute kidney injury, prolonged intubation, mediastinitis, surgical reopening, death). The state of sublingual microcirculation, of peripheral microcirculation and cardiovascular control will be assessed in 100 patients undergoing cardiac surgery during general anesthesia before the intervention and at the end of the intervention at the arrival in post-surgery ICU by means of signal processing techniques. The extracted markers will be used to assess a statistical prediction model of major morbidities.

Condition or disease

Cardiac Surgery

Coronary Artery Bypass Graft

Surgical Aortic Valve Replacement

Intervention/treatment

Acquisition of cardiovascular signals and microcirculation sidestream darkfield images

Study Type : Observational
Estimated Enrollment : 100 participants
Official Title : Micro- and Macro-Circulation in Cardiac Surgery Patients
Actual Study Start Date : March 2024
Estimated Primary Completion Date : March 2025
Estimated Study Completion Date : May 2025

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Criteria
Inclusion Criteria
  • age >18 yrs
  • indication for a cardiac surgery intervention
  • spontaneous sinus rhythm
  • informed consent
Exclusion Criteria
  • know autonomic nervous systems pathologies or dysfunctions
  • pregnancy

Micro- and Macro-Circulation in Cardiac Surgery Patients

Location Details


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Micro- and Macro-Circulation in Cardiac Surgery Patients

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Locations


Not yet recruiting

Italy, Milan

IRCCS Policlinico San Donato

San Donato Milanese, Milan, Italy, 20097

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