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NCT05703763 | NOT YET RECRUITING | Giant Cell Arteritis

The Applanation Tonometry in GCA Pilot
Sponsor:

Hospital of the Montreal Sacre-Coeur

Information provided by (Responsible Party):

Junbel Makhzum

Brief Summary:

The Applanation Tonometry in Giant Cell Arteritis (ATOM-GCA) study will answer the following questions: 1. How does PWV, measured by applanation tonometry of temporal arteries, differ between patients with and without a final diagnosis of GCA (based on pre-defined criteria 6 months after inclusion)? 2. What is the diagnostic accuracy and positivity cutoff of the PWV, measured by applanation tonometry, in detecting: 1. A clinical diagnosis of GCA (based on pre-defined criteria 6 months after inclusion)? 2. Inflammation of temporal arteries on high-resolution ultrasound? 3. What is the acceptability and adherence of repeat applanation tonometry during the follow-up period in patients with GCA?

Condition or disease

Giant Cell Arteritis

Intervention/treatment

Applanation tonometry

Standardized GCA assessment

Repeat applanation tonometry (optional)

Detailed Description:

ATOM-GCA is a single-center, cross-sectional vanguard study.

Study Type : OBSERVATIONAL
Estimated Enrollment : 146 participants
Official Title : The Applanation Tonometry in Giant Cell Arteritis Pilot
Actual Study Start Date : 2026-01
Estimated Primary Completion Date : 2026-10
Estimated Study Completion Date : 2027-03

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 50 Years to 99 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • 1. adult patient aged \> 50 years;
  • 2. referred for suspected, new-onset or relapsing cranial GCA;
  • 3. ability to understand and willingness to sign a written informed consent form.
Exclusion Criteria
  • 1. they had a temporal artery biopsy prior to the study visit;
  • 2. they used systemic glucocorticoids for ≥ 14 consecutive days in the previous 30 days.
The Applanation Tonometry in GCA Pilot

Location Details

NCT05703763

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

Not yet recruiting

Canada, Quebec

Vasculitis Clinic, Hospital of the Sacre-Coeur de Montreal

Montreal, Quebec, Canada, H4J1C5