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NCT05697874 | RECRUITING | Astroblastoma

International Rare Brain Tumor Registry
Sponsor:

Children's National Research Institute

Brief Summary:

The objective of the International Rare Brain Tumor Registry (IRBTR) is to better understand rare brain tumors through the collection of biospecimens and matched clinical data of children, adolescents, and young adult patients diagnosed with rare brain tumors.

Condition or disease

Astroblastoma

BCOR ITD Sarcoma

CNS Sarcoma

Unclassified Tumor, Malignant

Detailed Description:

The International Rare Brain Tumor Registry (IRBTR) is a prospective observational study that will collect tumor samples and matched clinical and radiological data to better understand the outcomes of patients with rare brain tumors in particular: CNS sarcoma, BCOR, MN-1 altered tumors, and other unclassified rare brain tumors. Data collected include demographics, disease characteristics, treatment information, radiological imaging, and biospecimen collection if available ( tumor tissues Patients will be followed longitudinally to obtain outcome data. Data collection will continue for approximately 10 years.

Study Type : OBSERVATIONAL
Estimated Enrollment : 5800 participants
Official Title : International Rare Brain Tumor Registry
Actual Study Start Date : 2023-01-01
Estimated Primary Completion Date : 2033-12
Estimated Study Completion Date : 2033-12

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: to 45 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patients with a known or suspected CNS Sarcoma.
  • * Patients with a known or suspected BCOR-altered brain tumor
  • * Patients with a known or suspected Astroblastoma/NM-1 altered brain tumor
  • * Patients with known or suspected histologically ambiguous/unclassifiable brain tumor
  • * Patients with a known or suspected rare brain tumor.
  • * Signed informed consent by patient/ parent or guardian (assent where applicable) to participate in the study.
Exclusion Criteria
  • * The patient has an extra-CNS primary tumor.
  • * The patient is older than 46 years of age at diagnosis.
  • * The patient or family is not willing to participate or does not sign informed consent.
International Rare Brain Tumor Registry

Location Details

NCT05697874

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, District of Columbia

Children's National Hospital

Washington, District of Columbia, United States, 20010