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NCT05694338 | RECRUITING | Gastrointestinal Cancer


Frailty in Patients With Gastrointestinal Cancer Who Are Undergoing Major Surgery
Sponsor:

The Guthrie Clinic

Brief Summary:

This research is for patients who have gastrointestinal cancer and have a planned major surgery. The purpose of this research is to identify cancer patients who may be at risk for frailty. Frailty is common in older adults and may include symptoms of weight loss, weakness, fatigue, low activity, slow walking and other illnesses. Frailty may increase the risk of problems after major surgery. The study will involve a survey, a blood sample, and a review of medical records.

Condition or disease

Gastrointestinal Cancer

Intervention/treatment

Frailty survey

Detailed Description:

The goals of the study are to: * Describe the rate of frailty in surgical cancer patients * Assess if frailty correlates with problems (adverse outcomes) after major surgery Participants taking part will be asked to complete a survey to assess frailty before surgery. The frailty survey is referred to as the Clinical Risk Analysis Index (RAI-C). Participants will have about 10 ml (2 teaspoons) of blood drawn before surgery. Blood tests will include complete blood count (CBC), vitamin A, creatinine, C-Reactive Protein (CRP), DHEA, albumin, and prealbumin.

Study Type : OBSERVATIONAL
Estimated Enrollment : 100 participants
Official Title : A Descriptive and Comparative Analysis of Frailty in Rural Versus Urban Cancer Patients Undergoing Major Surgical Oncologic Procedures
Actual Study Start Date : 2023-03-13
Estimated Primary Completion Date : 2026-06-01
Estimated Study Completion Date : 2027-06-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * 18 years old or older
  • * histologically proven gastrointestinal malignancy
  • * referral for elective major surgical procedures at including operations for upper and lower gastrointestinal malignancies and hepato-pancreato-biliary
  • * referral for neoadjuvant treatment followed by any of the above major surgical procedures
Exclusion Criteria
  • * under 18 years
  • * pregnant women

Frailty in Patients With Gastrointestinal Cancer Who Are Undergoing Major Surgery

Location Details

NCT05694338


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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


NOT YET RECRUITING

United States, New York

Guthrie Medical Group

East Corning, New York, United States, 14830

RECRUITING

United States, Pennsylvania

Robert Packer Hospital

Sayre, Pennsylvania, United States, 18840

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