Our Lady of Prado General Hospital
Francisco Rodríguez Argente
Immunomodulation of local immune response at the oropharyngeal mucosa can hypothetically activate mucosal immunity, which can difficult SARS-CoV-2 main immune evasion mechanisms in early stages of the disease and send an effective warning to the adaptive immune system. There are previous studies on immunotherapeutic management of upper respiratory tract infections with olive polyphenols. The investigators would like to study if participants following oromucosal immunomodulation with tiny quantities of high polyphenolic olive oil (early harvest olive oil) could have more possibilities to have less severe symptoms and a better outcome after SARS-CoV-2 infection.
COVID-19
High polyphenolic olive oil. (Early harvest olive oil).
NA
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 88 participants |
| Masking : | TRIPLE |
| Primary Purpose : | PREVENTION |
| Official Title : | Randomized and Controlled Clinical Trial for the Evaluation of the Efficacy and Safety of Oropharyngeal Immunoprophylaxis With Olive Oil Rich in Polyphenols as attenuation and prevention of the Infectious Disease Due to the SARS-CoV-2 Coronavirus. |
| Actual Study Start Date : | 2021-07-01 |
| Estimated Primary Completion Date : | 2022-09-30 |
| Estimated Study Completion Date : | 2022-09-30 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: | 1 |
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Not yet recruiting
Our Lady of Prado Hospital
Talavera de la Reina., Toledo, Spain, 45600