Thinking of joining a study?

Register your interest

Become a volunteer?

NCT05612048 | RECRUITING | Esophagogastric Cancer

A Study of Tooth Erosion in People With Esophagogastric Cancer
Sponsor:

Memorial Sloan Kettering Cancer Center

Brief Summary:

The researchers are doing this study to find out more about what may lead to the loss of tooth enamel (the thin outer covering of the tooth) and how often it happens in people with esophagogastric cancer, colorectal cancer, pancreatic cancer, breast cancer, head and neck cancer, or non-small cell lung cancer, or a healthy volunteer.

Condition or disease

Esophagogastric Cancer

Intervention/treatment

Survey

Intra-oral camera

Optional Salvia sample

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 300 participants
Masking : NONE
Primary Purpose : DIAGNOSTIC
Official Title : Pilot Study of Dental Erosion as a Non-invasive Biomarker of Esophagogastric Cancer
Actual Study Start Date : 2022-11-03
Estimated Primary Completion Date : 2025-11
Estimated Study Completion Date : 2025-11

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Subject is willing and able to provide written informed consent.
  • * Patients with a history of esophagogastric, HNSCC, PDAC, CRC, or NSCLC or healthy controls
  • * Patients must be able to fully comprehend and complete the survey and be willing to have pictures taken of their teeth with a camera or intra-oral camera.
  • * Patients must be able to understand English language or have access to adequate translation services.
  • * Age ≥ 18 years old.
Exclusion Criteria
  • * Subjects without evaluable molars or with significant molar dental work precluding dentists from assessing enamel status, Note: evaluable is defined as having bilateral assessable mandibular molars, or erosions present in the remaining assessable quadrants.
  • * For healthy controls only, patients cannot have a non-skin cancer history nor presenting for a procedure evaluating reflux symptoms.
A Study of Tooth Erosion in People With Esophagogastric Cancer

Location Details

NCT05612048

Please Choose a site

How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, New York

Memorial Sloan Kettering Cancer Center (All Protocol Activities)

New York, New York, United States, 10065