University of Chicago
The purpose of this study is to determine whether or not Magnetic Resonance Images (MRI) will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer.
Prostate Cancer Screening
Prostate MRI
NA
In this study the study team hypothesizes MR images will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer. Subjects will receive gadolinium (intravenous contrast agent) as part of their research MRI exam. While the deposition of gadolinium (Gd) has been demonstrated in numerous studies, the clinical consequences of Gd deposition are unknown. Gd enhanced MRI scans provide crucial medical information regarding prostate and prostate cancer imaging and contrast-enhanced images are a component of all guidelines and the PIRADS scoring system. The study team will compare baseline prostate MR images of men at high risk of developing prostate cancer to those without an identifiable predisposition and evaluate the role of a GRS in screening men with at elevated risk of being diagnosed with prostate cancer.
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 250 participants |
| Masking : | NONE |
| Primary Purpose : | SCREENING |
| Official Title : | MRI Screening in Men at High Risk of Developing Prostate Cancer |
| Actual Study Start Date : | 2022-03-02 |
| Estimated Primary Completion Date : | 2037-03-01 |
| Estimated Study Completion Date : | 2039-03-01 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years |
| Sexes Eligible for Study: | MALE |
| Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
University of Chicago
Chicago, Illinois, United States, 60637
RECRUITING
NorthShore University Health System - Glenbrook Hospital
Glenview, Illinois, United States, 60026