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NCT05535894 | RECRUITING | Pancreatic Cancer

Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
Sponsor:

West Virginia University

Information provided by (Responsible Party):

Shailendra Singh

Brief Summary:

This study aims to evaluate the EUS-RFA in terms of efficacy for pain management and improvement in quality-of-life parameters for patients with advanced inoperable pancreatic cancer. The primary objectives of this study are to 1) evaluate the utility of EUS-RFA for pain control and improvement in quality-of-life parameters for patients with advanced pancreatic cancer; 2) to measure the reduction of analgesic medications' requirements in patients affected by inoperable pancreatic cancer.

Condition or disease

Pancreatic Cancer

Intervention/treatment

Ablation of Celiac Ganglion

Study Type : OBSERVATIONAL
Estimated Enrollment : 12 participants
Official Title : Endoscopic Ultrasound-guided Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
Actual Study Start Date : 2022-08-10
Estimated Primary Completion Date : 2025-12
Estimated Study Completion Date : 2025-12

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Diagnosis of pancreatic cancer based on clinical, radiological, or pathological assessment;
  • * Referred for abdominal and/or back pain due to pancreatic cancer;
  • * No prior history of RFA;
  • * Cancer pain unresponsive to the WHO 3-step analgesic ladder;
  • * Willingness to consent to participate in the study.
Exclusion Criteria
  • * Patients who are not willing to give informed consent or agree to participate in the study
  • * Surgically resectable pancreatic cancer;
  • * Abdominal pain with etiology other than pancreatic malignancy;
  • * Evidence of concurrent infection;
  • * Patients with irreversible coagulopathy international normalized ratio \>1.5 or platelet count \<50,000/mm3),
  • * Patients with a preliminary diagnosis of adenocarcinoma are not possible established with intraprocedural at EUS-guided FNA.
Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer

Location Details

NCT05535894

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How to Participate

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Locations

RECRUITING

United States, West Virginia

Shailendra Singh

Morgantown, West Virginia, United States, 26508