Shanghai University of Traditional Chinese Medicine
Asthma is one of the most common chronic respiratory diseases. Previous study found a series of differentially expressed genes and proteins (transgelin-2, metallothionein-2, ezrin) in asthmatic rat. The aim of the study is to investigate the changes and associations of these gene with asthma in human.
Asthma
No intervention
This study will investigate the changes and associations in asthma. In this project, the investigators will explore the changes of gene expression of transgelin-2, metallothionein-2 and ezrin in asthma and investigate their correlation with current diagnosis markers of asthma, including pulmonary function, fractional exhaled nitric oxide,eosinophil counts,immunoglobulin E, interleukin-5, etc.
Study Type : | Observational |
Estimated Enrollment : | 100 participants |
Official Title: | The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma: A Case-control Study |
Actual Study Start Date : | August 2022 |
Estimated Primary Completion Date : | August 2024 |
Estimated Study Completion Date : | August 2025 |
Information not available for Arms and Intervention/treatment
Ages Eligible for Study: | 14 Years to 75 Years |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Accepts Healthy Volunteers |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Not yet recruiting
Xiangya Hospital, Central South University
Changsha, Hunan, China, 410000
Not yet recruiting
Yueyang Hospital, Shanghai University of Traditional Chinese Medicine
Shanghai, Shanghai, China, 200030