Nīmes University Hospital Center
Charcot foot, characterized by progressive destructive damage to bone, soft tissue and tendons, involving joint dislocation in the ankle and foot, is a complication of diabetes that is still poorly understood by patients and caregivers. The clinical signs are non-specific and it is therefore largely underestimated due to a delay in diagnosis/lack of diagnosis.This study will be on a prospective multicenter cohort of patients with chronic Charcot's foot in France to evaluate the evolution of quality of life at 2 years, as well as predictive factors in order to better identify subjects with the worst outcome among this population. Our hypothesis is that, in patients with chronic Charcot foot, the deterioration in quality of life over time is primarily related to loss of foot and ankle functionality, foot and ankle deformity and the presence of foot wounds/comorbidities/severe diabetic complications.
Charcot Joint of Foot
Osteoarthropathy
Filling in the SF-36, FAAM-F, PHQ-9, PHQ-2 and the simplified version of the EPICES score questionnaire
Diabetes mellitus is a chronic disease, representing a major public health problem. An estimated 537 million people have diabetes. Charcot foot, also known as neurogenic osteoarthropathy (NAO), is one of the complications of diabetes secondary to diabetic neuropathy. It is characterized by progressive destructive damage to bone, soft tissue and tendons, involving joint dislocation in the ankle and foot. Charcot foot is a complication of diabetes that is still poorly understood by patients and caregivers, with non-specific clinical signs. It is therefore largely underestimated, since it is estimated that there is a delay in diagnosis or a lack of diagnosis in approximately 25% of cases. The objective of our study is to conduct a prospective multicenter cohort of patients with chronic Charcot's foot in France in order to evaluate the evolution of the quality of life at 2 years, as well as its predictive factors. In this way, we will be better able to identify the subjects with the worst outcome among the chronic Charcot foot population. Our hypothesis is that the deterioration in quality of life over time in patients with chronic Charcot foot is primarily related to loss of foot and ankle functionality, foot and ankle deformity, the presence of foot wounds and/or comorbidities or severe diabetic complications.
| Study Type : | OBSERVATIONAL |
| Estimated Enrollment : | 150 participants |
| Official Title : | Factors Associated With Quality of Life Outcomes in Diabetic Patients With Chronic Wound-free Charcot Foot |
| Actual Study Start Date : | 2023-01-23 |
| Estimated Primary Completion Date : | 2027-07-22 |
| Estimated Study Completion Date : | 2028-01-22 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
NOT YET RECRUITING
Boulogne-sur-Mer Hospital Center
Boulogne-sur-Mer, Pas-de-Calais, France, 62200
NOT YET RECRUITING
Eastern Hospital Group, Cardiological Hospital Diabetology Department 28 Av du Doyen Lépine
Bron, France, 69500
NOT YET RECRUITING
CH Sud Francilien Diabetology Department 40 Avenue Serge Dassault
Corbeil-Essonnes, France, 91100
NOT YET RECRUITING
Grenoble University Hospital Department of Endocrinology Allée des Sablons Les écrins
Grenoble, France, 38043
NOT YET RECRUITING
Hospital Hôtel Dieu Endocrinology Department 26 rue d’Harfleur
Le Creuset, France, 71200
RECRUITING
CHU Bicêtre Department of Endocrinology and Reproductive Diseases 78 rue du Général Leclerc
The Kremlin-Bicêtre, France, 94275
RECRUITING
CH of Lens Unit of Diabetology-Endocrinology-Nutrition-Obesity Hospital Center Dr SCHAFFNER 99 rte de La Bassée,
Lens, France, 62307
NOT YET RECRUITING
CHRU of Lille Department of Endocrinology Diabetology and Metabolism, Claude Huriez Hospital, Rue Polonovski
Lille, France, 59037
NOT YET RECRUITING
CHU de la CONCEPTION Department of Nutrition, Diabetology, Medical and surgical obesity 47 Bd Baille
Marseille, France, 13005
RECRUITING
Montpellier University Hospital Department of Metabolic Diseases 371 av. Dean Giraud
Montpellier, France, 34295
RECRUITING
GH Pitié Salpétrière Podiatry Unit Diabetology Department 47-83 Bd de l’Hôpital
Paris, France, 750013
RECRUITING
GH Paris Saint Joseph Department of Diabetology and Endocrinology 185 rue Raymond Losserand
Paris, France, 75014
NOT YET RECRUITING
Cochin Hospital Diabetology Department 123 Bd de Port Royal
Paris, France, 75014
RECRUITING
Lyon Sud University Hospital Department of Endocrinology-Diabetes-Nutrition CH Lyon Sud Medical Pavilion, Bat 1B 165 chemin du Grand Revoyet
Pierre-Bénite, France, 69495
RECRUITING
CHU Reims Department of Endocrinology, diabetes-nutrition Rue du Général Koenig
Reims, France, 51092
NOT YET RECRUITING
University Hospitals of Strasbourg Department of Endocrinology and Diabetology 1, place de l’Hôpital,
Strasbourg, France, 61091
RECRUITING
DRON Hospital Diabetology Department 135 rue du Président Coty
Tourcoing, France, 52208