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NCT05396612 | RECRUITING | Breast Cancer


Role of the Immune Environment in Response to Therapy in Breast Cancer
Sponsor:

Abramson Cancer Center at Penn Medicine

Information provided by (Responsible Party):

Jennifer Zhang

Brief Summary:

This is an observational case-control study of tissues collected from women with ER+HER2- breast cancers. The immune environments of these cancers will be compared to triple negative and HER2+ breast cancers. No randomization or changes to standard of care treatment will occur as part of the study.

Condition or disease

Breast Cancer

Are positive breast cancer

HER2-negative Breast Cancer

TNBC - Triple-Negative Breast Cancer

Intervention/treatment

Collection of personal health information from women treated at the University of Pennsylvania under an approved HIPAA waiver.

Study Type : OBSERVATIONAL
Estimated Enrollment : 300 participants
Official Title : Role of the Immune Environment in Response to Therapy in Breast Cancer
Actual Study Start Date : 2022-10-03
Estimated Primary Completion Date : 2032-12-31
Estimated Study Completion Date : 2032-12-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers:
Criteria
Inclusion criteria
  • Women 18 years of age or older with non-metastatic breast cancer undergoing surgical resection in the University of Pennsylvania Health System.
  • Exclusion criteria
    • Males Children Pregnant individuals

Role of the Immune Environment in Response to Therapy in Breast Cancer

Location Details

NCT05396612


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How to Participate

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Locations


RECRUITING

United States, Pennsylvania

Abramson Cancer Center

Philadelphia, Pennsylvania, United States, 19104

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