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NCT05277025 | RECRUITING | Fibromyalgia


Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Sponsor:

University of Florida

Brief Summary:

Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.

Condition or disease

Fibromyalgia

Rheumatoid Arthritis

Study Type : OBSERVATIONAL
Estimated Enrollment : 150 participants
Official Title : Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Actual Study Start Date : 2022-03-22
Estimated Primary Completion Date : 2026-02-28
Estimated Study Completion Date : 2026-02-28

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 70 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Ages 18-70
  • * Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM
  • * Fulfills the 2010 ACR-EULAR classification criteria for RA
  • * Healthy volunteers: No significant pain/fatigue/depression/anxiety.
Exclusion Criteria
  • * Diabetes
  • * Cancer
  • * Advanced liver, kidney or cardiovascular disease
  • * Neuropathic pain

Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes

Location Details

NCT05277025


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Locations


RECRUITING

United States, Florida

University of Florida

Gainesville, florida, United States, 32610

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