University Hospital, Ghent
Urinary incontinence is the most frequently observed lower urinary tract symptom (LUTS) in children with cerebral palsy (CP) (Samijn et al., 2016). Higher brain centers responsible for bladder function may be related to the presence of incontinence. The current pilot study is the first study of a research project focusing on correlations between brain damage and incontinence.
fMRI Research
invasive urodynamic evaluation
functional magnetic resonance imaging during bladder filling
NA
Urinary incontinence is the most frequently observed lower urinary tract symptom (LUTS) in children with cerebral palsy (CP) (Samijn et al., 2016). Being more or completely dry could improve the quality of life and health status of the child and the social environment. Higher brain centers responsible for bladder function may be related to the presence of incontinence. These higher brain centers could be correlated to the brain damage seen in children with CP. The current pilot study is the first study of a research project focusing on correlations between brain damage and incontinence. The study wants to validate if the defined fMRI paradigm can provide correct information concerning brain activity during bladder filling, to ensure usable results and comply with ethical demands for testing in children, the protocol will be tested and results validated during the pilot study with healthy adults. During the fMRI study, the bladder will be filled until FSF and NDV. Functional MRI-data will be obtained during the filling and emptying phase of the bladder on both volumes
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 6 participants |
| Masking : | NONE |
| Primary Purpose : | SCREENING |
| Official Title : | Pilot Study: Apllicability of an fMRI Protocol for Incontinence Research |
| Actual Study Start Date : | 2025-05-01 |
| Estimated Primary Completion Date : | 2026-09-30 |
| Estimated Study Completion Date : | 2026-09-30 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 20 Years to 35 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: | 1 |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Not yet recruiting
Ghent University Hospital
Ghent, Flanders, Belgium, 9000