Massachusetts General Hospital
Al -Jawahiri, Areej, M.
This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).
Relapsed Adult AML
Primary Refractory Acute Myeloid Leukemia
High Risk Acute Myeloid Leukemia
Specialty Palliative Care
Primary Palliative Care
NA
Patients with newly diagnosed AML confront a sudden and life-threatening diagnosis, requiring an immediate disruption of their life and an urgent hospitalization to begin therapy. During their hospitalization for chemotherapy, patients with AML often experience difficult physical symptoms that negatively impact their quality of life and physical function. Patients with AML also experience significant psychological distress as they combat the abrupt onset of illness, uncertainty regarding their prognosis, physical and social isolation during hospitalization, and complete loss of independence. The abrupt onset of these symptoms can be distressing to both the patient and their family and friends (also called "caregivers"). Research has shown that early involvement of a team of clinicians specializing in lessening (or "palliating") these physical and emotional symptoms and helping patients and their caregivers cope with AML improves their quality of life and experience with their illness. This team is called "specialty palliative care" and consists of physicians and advanced practice providers who work closely and collaboratively with the oncology team to care for patients and caregivers. Research has also shown that training oncology clinicians to incorporate palliative care skills into their practice, called "primary palliative care," is an alternative strategy to having specialty palliative care clinicians care for patients with leukemia. The purpose of this study is to determine whether specialty palliative care or primary palliative care is the best way to improve the quality of life and experience of patients with AML and their caregivers. This study will randomly assign hospitals to deliver either specialty palliative care or primary palliative care for patients with AML. Participants in this study will receive either specialty or primary palliative care during their hospital stays based upon which strategy their hospital has been assigned to. Participants assigned to specialty palliative care will be care for by both oncology and palliative care clinicians during their hospital stays for AML. Participants assigned to primary palliative care will be cared for by oncology clinicians who have been trained in palliative care during their hospital stays for AML.
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 2300 participants |
| Masking : | NONE |
| Primary Purpose : | SUPPORTIVE_CARE |
| Official Title : | Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia |
| Actual Study Start Date : | 2022-06-01 |
| Estimated Primary Completion Date : | 2028-04 |
| Estimated Study Completion Date : | 2029-04 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years to 120 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: | 1 |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
ACTIVE NOT RECRUITING
University of Alabama - Birmingham
Birmingham, Albama, United States, 35294
ACTIVE NOT RECRUITING
Stanford University
Stanford, California, United States, 94305
ACTIVE NOT RECRUITING
University of Colorado Denver I Anschutz Medical Campus
Denver, Colorado, United States, 80204
ACTIVE NOT RECRUITING
University of Miami
Miami, Florida, United States, 33146
ACTIVE NOT RECRUITING
Moffitt Cancer Center
Tampa, Florida, United States, 33612
NOT YET RECRUITING
Emory University
Atlanta, Georgia, United States, 30322
ACTIVE NOT RECRUITING
Northwestern University
Evanston, Illinois, United States, 60208
NOT YET RECRUITING
Indiana University
Bloomington, Indiana, United States, 47405
NOT YET RECRUITING
Johns Hopkins University
Baltimore, Maryland, United States, 21218
RECRUITING
Massachusetts General Hospital
Boston, Massachusetts, United States, 02115
RECRUITING
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02215
RECRUITING
Mayo Clinic
Rochester, Minnesota, United States, 55905
ACTIVE NOT RECRUITING
University of Rochester
Rochester, New York, United States, 14627
NOT YET RECRUITING
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States, 27599
RECRUITING
Duke University
Durham, North Carolina, United States, 27708
ACTIVE NOT RECRUITING
Ohio State University
Columbus, Ohio, United States, 43210
ACTIVE NOT RECRUITING
Oregon Health & Science University
Portland, Oregon, United States, 97239
RECRUITING
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
ACTIVE NOT RECRUITING
Fred Hutchinson Cancer Center
Seattle, Washington, United States, 98109
ACTIVE NOT RECRUITING
University of Wisconsin
Madison, Wisconsin, United States, 53715