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NCT04977830 | RECRUITING | Thoracic Insufficiency Syndrome


Pulmonary Assessment in Thoracic Insufficiency Syndrome Patients
Sponsor:

Children's Hospital of Philadelphia

Brief Summary:

Thoracic insufficiency syndrome (TIS) is a complex condition that involves chest wall deformities that can affect normal breathing and lung growth. In most cases, children with TIS are also born with spine disorders such as scoliosis. The inability of the thorax to support normal respiration or lung growth can cause respiratory distress and even mortality. Investigators aim to validate MRI imaging sequences to use as an assessment tool for pulmonary function.

Condition or disease

Thoracic Insufficiency Syndrome

Intervention/treatment

Xenon-129

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 5 participants
Masking : NONE
Primary Purpose : BASIC_SCIENCE
Official Title : New Strategies for Pulmonary Assessment in Spinal and Chest Wall Deformity
Actual Study Start Date : 2025-12
Estimated Primary Completion Date : 2026-08-30
Estimated Study Completion Date : 2026-08-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 6 Years to 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Males or females 6 to 18 years old diagnosed with thoracic insufficiency syndrome who are undergoing surgery
Exclusion Criteria
  • * patients not diagnosed with thoracic insufficiency syndrome

Pulmonary Assessment in Thoracic Insufficiency Syndrome Patients

Location Details

NCT04977830


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Locations


RECRUITING

United States, Pennsylvania

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

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