Danish Headache Center
Lili Kokoti
To investigate the hemodynamic effects of PACAP38 after glibenclamide administration.
Migraine
Headache
Pain
glibenclamide
PACAP38
NA
22 healthy participants will randomly be allocated to receive PACAP38 infusion followed by glibenclamide or placebo on two different days. The aim of the study is to investigate the vascular effect of PACAP38 after glibenclamide administration. Repeated measurements covering the arteria radialis (RA), superficial temporal artery (STA) and middle cerebral artery (MCA) before and after PACAP38 infusion and glibenclamide/placebo administration
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 22 participants |
| Masking : | QUADRUPLE |
| Primary Purpose : | OTHER |
| Official Title : | The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy Volunteers |
| Actual Study Start Date : | 2020-10-20 |
| Estimated Primary Completion Date : | 2021-03-19 |
| Estimated Study Completion Date : | 2021-03-19 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 18 Years to 60 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: | 1 |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
Not yet recruiting
Danish Headache Center
Copenhagen, Capital Region, Denmark, 2600