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NCT04949087 | RECRUITING | Arthritis Shoulder


Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)
Sponsor:

Rush University Medical Center

Brief Summary:

The purpose of this study is to compare the efficacy of intra-articular corticosteroid injections versus platelet-rich plasma injections for non-operative treatment of primary glenohumeral osteoarthritis. The efficacy of intra-articular injections, outside of hyaluronic acid, for the treatment of glenohumeral OA is not known, yet these treatments are commonly used with hopes of providing patients with symptomatic relief that can hopefully delay or prevent the need for shoulder arthroplasty. This study will help elucidate the therapeutic benefit of corticosteroid and Platelet Rich Plasma (PRP) injections in this patient population.

Condition or disease

Arthritis Shoulder

Intervention/treatment

Glenohumeral Injection

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 200 participants
Masking : TRIPLE
Masking Description : Double-blinded, randomized
Primary Purpose : TREATMENT
Official Title : Prospective, Double Blind, Randomized Control Trial Comparing the Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis
Actual Study Start Date : 2023-03-13
Estimated Primary Completion Date : 2025-01
Estimated Study Completion Date : 2026-01

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Patient ≥18y.o. of age
  • * Primary glenohumeral arthritis (bone on bone or near bone on bone) that has been previously diagnosed on radiographs and clinical evaluation.
  • * Baseline pain level of VAS \>4
Exclusion Criteria
  • * Secondary causes of arthritis (i.e. septic arthritis, rheumatoid arthritis, rotator cuff arthropathy, post-traumatic arthritis)
  • * Ipsilateral shoulder surgery within 1 year
  • * Any glenohumeral joint injection within 3 months
  • * Allergy to lidocaine
  • * Known pregnancy
  • * Workers compensation case regarding shoulder

Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)

Location Details

NCT04949087


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Locations


RECRUITING

United States, Illinois

Rush University Medical Center

Chicago, Illinois, United States, 60612

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