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NCT04915105 | NOT YET RECRUITING | Dermatologic Disease


Personal Precise Treatment on Psoriasis and Psoriatic Arthritis
Sponsor:

Taichung Veterans General Hospital

Brief Summary:

Part of psoriasis and psoriatic arthritis patients treated with biologics and met primary failure. Therefore, we are going to create a cell based platform to evaluate the treatment effects of different biologics on psoriasis and psoriatic arthritis patients before prescribed by physicians

Condition or disease

Dermatologic Disease

Intervention/treatment

Markers data from PBMCs

Phase

NA

Detailed Description:

PBMCs isolated from psoriasis and psoriatic arthritis and incubated with Group A streptococcus and different biologics for 24 hours. Cytokines expression in the culture supernatants will be measured and the data can be reference for physician's prescription.

Study Type : INTERVENTIONAL
Estimated Enrollment : 90 participants
Masking : NONE
Primary Purpose : SCREENING
Official Title : Personal Precise Treatment on Psoriasis and Psoriatic Arthritis and Investigate the Mechanisms of Biological Agents Induced Systemic Lupus Erythematosus
Actual Study Start Date : 2021-05-31
Estimated Primary Completion Date : 2025-05-31
Estimated Study Completion Date : 2025-05-31

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 20 Years to 70 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * 1. Healthy control without underline disease such as psoriasis and psoriatic arthritis. 2. Psoriasis been diagnosed for over six months and PASI \>10. 3.Psoriatic arthritis been diagnosed for over six months and \>1 swallow and tender joints
Exclusion Criteria
  • * nil

Personal Precise Treatment on Psoriasis and Psoriatic Arthritis

Location Details

NCT04915105


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