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NCT04742439 | RECRUITING | tDCS

Individualizing tDCS Dose
Sponsor:

Medical University of South Carolina

Information provided by (Responsible Party):

Kevin Caulfield

Brief Summary:

Transcranial direct current stimulation (tDCS) is a noninvasive method of modulating brain activity and has therapeutic potential in many neurological and psychiatric conditions. However, unlike every current FDA-approved form of brain stimulation, there is no method of individualizing stimulation dose. In this study, a method of individualizing tDCS dose on behavioral outcomes and whether this could help to improve the consistency and magnitude of the stimulation effects will be tested.

Condition or disease

tDCS

Motor Function

Intervention/treatment

Sham transcranial direct current stimulation

Individualized transcranial direct current stimulation

2mA transcranial direct current stimulation

4mA transcranial direct current stimulation

Phase

NA

Study Type : INTERVENTIONAL
Estimated Enrollment : 70 participants
Masking : TRIPLE
Primary Purpose : BASIC_SCIENCE
Official Title : Testing the Effects of Individualized and 4mA tDCS
Actual Study Start Date : 2024-12-31
Estimated Primary Completion Date : 2025-12-31
Estimated Study Completion Date : 2026-04-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years to 80 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: 1
Criteria
Inclusion Criteria
  • * Healthy volunteers or chronic stroke participants (at least 6 months prior to the study)
  • * No history of epilepsy
  • * No metal in the body
  • * No contraindications for TMS or MRI scanning
  • * Right handed
  • * Ability to find motor hotspot and acquire motor evoked potentials
Exclusion Criteria
  • * Metal in the body
  • * History of epilepsy or claustrophobia
  • * Alcohol or substance abuse or dependence
  • * Current treatment for any psychiatric conditions (pharmacological or otherwise)
  • * Pregnant or actively breastfeeding
Individualizing tDCS Dose

Location Details

NCT04742439

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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations

RECRUITING

United States, South Carolina

Medical University of South Carolina

Charleston, South Carolina, United States, 29425