Icahn School of Medicine at Mount Sinai
Mary C Sano
This study compares different music therapy (MT) experiences and their impact on memory and language in patients with Alzheimer's disease and Mild Cognitive Impairment. The 12-month study will assess the role of common experiences involving familiar music and other pleasant events (blinded control) to benefit cognition and measure the quality of life for people with Alzheimer's disease and Mild Cognitive Impairment. Following screening, all participants will meet with a licensed music therapist at the first study visit. Thereafter, each group will have an individualized schedule of follow-up telephone calls and visits. Screening for the study and participation in the study intervention can be completed in-person or from your home, if you do not live in the area.
Alzheimer's Disease
Mild Cognitive Impairment
Home-based MT through Supervised, Supported Singing (H3S)
Individualized Music Therapy (IMT)
Attention Control (AtCon)
NA
Interested participants and their study partner will be enrolled after an evaluation to determine cognitive impairment or mild dementia. The evaluation, either in person or remote, will include cognitive testing, clinical and neurological evaluation, a review medical records and medical history and an examination as deemed necessary by a dementia physician. Eligible participants will undergo baseline testing including linguistic analyses and will be randomly assigned to one of 3 intervention groups. Participants and their study partners will be contacted at least once every three months for cognitive testing and medical review. Contact with the music therapy team will occur up to twice per week but not less than once per month, for the first six months study enrollment.
| Study Type : | INTERVENTIONAL |
| Estimated Enrollment : | 100 participants |
| Masking : | TRIPLE |
| Masking Description : | All treatment arms will be conducted at the Louis Armstrong Center for Music and Medicine with staff at that location while screening and all outcome evaluations will be conducted at the Alzheimer's Disease Research Center at the Mount Sinai location. A single unblinded team member at each site will coordinate visits and data collection. |
| Primary Purpose : | TREATMENT |
| Official Title : | A Randomized, Blinded, Controlled Trial of Music Therapy Singing Interventions for Patients With MCI and AD |
| Actual Study Start Date : | 2019-08-27 |
| Estimated Primary Completion Date : | 2025-07 |
| Estimated Study Completion Date : | 2025-07 |
Information not available for Arms and Intervention/treatment
| Ages Eligible for Study: | 55 Years |
| Sexes Eligible for Study: | ALL |
| Accepts Healthy Volunteers: |
Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.
RECRUITING
Louis Armstrong Center for Music and Medicine, Mount Sinai Beth Israel
New York, New York, United States, 10003
RECRUITING
Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029