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NCT04620226 | RECRUITING | Hepatitis C


UHN Inpatient Hepatitis C & B Screening
Sponsor:

Jordan Feld

Information provided by (Responsible Party):

Jordan Feld

Brief Summary:

Currently, there is a lack of literature on programs evaluating rapid screening methods to traditional venipuncture methods for sample collection during screening for viral hepatitis. Due to the relatively low diagnosis and linkage to care rate, screening programs that provide same day results for viral hepatitis infection may improve both diagnosis and enable providers to engage patients shortly after diagnosis. This stands in contrast to the multi-visit, weeks long process that normally accompanies serum testing for hepatitis C virus (HCV) and hepatitis B virus (HBV). A few American studies have examined the implementation of HCV inpatient screening programs; however, they are focused specifically on high-risk patient populations, the barriers to accessing care experienced by study participants are not relevant to the Canadian healthcare system context, and do not use rapid testing. Furthermore, there are few, if any, data on HBV inpatient screening programs and the diagnosis rate remains low. This project will provide key data on a rapid inpatient screening and linkage to care strategy as well as the prevalence of these viruses across different age bands within the population. Finally, the study will help determine whether rapid inpatient screening is a feasible and acceptable approach for screening and linkage to care.

Condition or disease

Hepatitis 100

Hepatitis B

Intervention/treatment

Quality Improvement

Phase

PHASE4

Study Type : INTERVENTIONAL
Estimated Enrollment : 2920 participants
Masking : NONE
Primary Purpose : SCREENING
Official Title : Screening for Hepatitis C and Hepatitis B in Inpatients: A Toronto Viral Hepatitis Care Network (VIRCAN) Collaboration
Actual Study Start Date : 2024-02-01
Estimated Primary Completion Date : 2025-07
Estimated Study Completion Date : 2025-07

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * Adults aged 18 years or older at time of consent
  • * Patients admitted to GIMIUs at TGH or TWH
Exclusion Criteria
  • * Patients whose end of life is expected to be less than 6 months
  • * Patients who are unable or decline to provide informed consent
  • * Patients with confirmed, active COVID-19 infections
  • * Patients with immediate life-threatening conditions where screening for chronic HCV and HBV infection may delay urgent care

UHN Inpatient Hepatitis C & B Screening

Location Details

NCT04620226


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How to Participate

Want to participate in this study, select a site at your convenience, send yourself email to get contact details and prescreening steps.

Locations


RECRUITING

Canada, Ontario

Toronto General Hospital

Toronto, Ontario, Canada, M5G 2C4

RECRUITING

Canada, Ontario

Toronto Western Hospital

Toronto, Ontario, Canada, M5T 2S8

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