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NCT04497766 | COMPLETED | Asthma in Children


Comparasion of Efficacy of Nebulized With Intravenous Magnesium Sulphate in Children With Asthma
Sponsor:

Saima Khatoon

Information provided by (Responsible Party):

Saima Khatoon

Brief Summary:

The purpose of study is to assess the effectiveness of nebulized magnesium sulphate in children presenting with acute asthma.Study perfoma consists of demographic variables,exclusion criteria and pediatric asthma score that includes respiratory rate,SPO2 at room air(requirement of oxygen),auscultatory findings in chest,dysnea and retractions.

Condition or disease

Asthma in Children

Intervention/treatment

Nebulized Magnesium sulfate

Intravenous magnesium sulphate

Phase

PHASE4

Detailed Description:

After getting informed consent from guardian,148 patients of acute moderate ro severe asthma with pediatric asthma score 8-15 will be randomly classified into 2 groups and one group will receive nebulization with magnesium sulphate and other will receive intravenous magnesium sulphate and effectiveness will be compared by 4 point reduction in PAS from baseline in either groups after 6 hours.

Study Type : INTERVENTIONAL
Estimated Enrollment : 148 participants
Masking : SINGLE
Primary Purpose : TREATMENT
Official Title : Comparasion of Efficacy of Nebulized Magnesium Sulphate With Intravenous Magnesium Sulphate in Children With Acute Asthma
Actual Study Start Date : 2019-10-01
Estimated Primary Completion Date : 2020-09-30
Estimated Study Completion Date : 2020-09-30

Information not available for Arms and Intervention/treatment

Ages Eligible for Study: 2 Years to 12 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers:
Criteria
Inclusion Criteria
  • * patients with age 2 to 12 years with acute moderate to severe exacerbation of asthma as per operational definition children who are unrespoinsive to standard treatment of asthma at 60 minutes
Exclusion Criteria
  • * those with history of chronic lung disease and abnormal renal function contraindication for MgSO4 due to hepatic or renal disease allergy to MgSo4 children who has other comorbid illness

Comparasion of Efficacy of Nebulized With Intravenous Magnesium Sulphate in Children With Asthma

Location Details

NCT04497766


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Locations


Not yet recruiting

Pakistan, Punjab

King edward medical university/mayo hospital lahore

Lahore, Punjab, Pakistan, 56000

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